Here is the list of 88 drugs marketed in France considered "dangerous"

Here is the list of 88 drugs marketed in France considered “dangerous”

The specialized magazine “Prescrire” made public, this Wednesday, December 7, its 2023 report on drugs to be discarded. A total of 107 substances appear on this list, 88 of which are marketed in France.

Prescrire magazine published, this Wednesday, December 7, the list of drugs to be discarded “for better care.” Thus, 107 medicines stand out, of which 88 are marketed in France.


The list of drugs that Prescrire advises to avoid caring and replacing with better options evolves every year, taking into account the progress of knowledge.

To read at ➡

— Prescribe (@RevuePrescrire) November 29, 2022

All have a marketing authorization, French or European, and “Prescrire” has subjected them to a rigorous evaluation based on desk research, efficacy criteria relevant to patients and consideration of adverse effects.

Drugs that are more dangerous than useful

The 107 drugs reported by the specialized magazine thus present “an unfavorable benefit-risk balance in all clinical situations in which they are authorized.”

Specifically, these drugs are considered more dangerous than helpful. Sometimes it can just be a specific form or dosage. The specialized magazine, whose articles are mostly written by health professionals, explains, case by case, the reason for the unfavorable benefit-risk balances. Whenever possible, alternatives that are more beneficial to patients are offered.

Also read:
The shortage of medicines intensifies in pharmacies: here is the list of affected products

The 88 drugs marketed in France “to be discarded”

Drugs used in hematology and for transplants
Defibrotide (Defitelio)

Antitumor drugs
Panobinostat (Farydak)
Trabectedin (Yondelis or others)
Vandetanib (Caprelsa)
Vinflunine (Javlor)

Medications prescribed in cardiology
Bezafibrate (Befizal)
Ciprofibrate (Lipanor or other)
Fenofibrate (lipantyl or other)
Dronedarone (Multaq)
Ivabradine (Procoralan or other)
Nicorandil (Ikorel or other)
Olmesartan (Alteis, Olmetec, Alteisduo, Coolmetec, Axeler, Sevikar)
Trimetazidine (Vastarel or other)

Drugs used in dermatology and against allergies.
Finasteride 1mg (Propecia or other)

Mequitazine (Primalan)
Dermal tacrolimus (Protopic or other)
Promethazine injection (Phenergan)

diabetes medications
Gliptins: alogliptin (Vipidia, Vipdomet), linagliptin (Trajenta, Jentadueto), saxagliptin (Onglyza, Komboglyze), sitagliptin (Januvia, Xelevia, Janumet, Velmetia), and vildagliptin (Galvus, Eucreas)

Medications used to lose weight.
Orlistat (Xenical or other)

Certain nonsteroidal anti-inflammatory drugs
Aceclofenac (Cartrex or other)
Oral diclofenac (Voltaren or other)
Coxibs: celecoxib (Celebrex or other), etoricoxib (Arcoxia or other), and parecoxib (Dynastat)
Ketoprofen gel (Ketum gel or other)
Meloxicam (Mobic or other)
Piroxicam (Feldene or other)
Systemic Tenoxicam (Tilcotil)

Osteoarthritis Medications
Diacerein (Art 50 or other)
Glucosamine (Flexea or other)

muscle relaxants
Methocarbamol (Lumirelax)
Thiocolchicoside (Miorel or other)

Osteoporosis medications
Denosumab 60mg (Prolia)

Drugs used in rheumatology
Capsaicin patches (Qutenza)
The combination of colchicine, opium powder and thiemonium (Colchimax)
Quinine (hexaquine, Okimus)

Drugs used in gastroenterology

Obeticholic Acid (Ocaliva)
Medicinal clays: diosmectite (Smecta or others), hydrotalcite (Rennieliquo), beidellitic montmorillonite or monmectite (Beldelix, Gelox) and kaolin (Gastropax, Neutroses)
Domperidone (Motilium or other)
Droperidol (Droleptan or other)
Metopimazine (Vogalene, Vogalib)
Prucalopride (Resolor)
Opium Tincture (Dropizal)
Glyceryl Trinitrate Ointment 0.4% (Rectogesic)

Drugs used in gynecology and endocrinology.
Tibolone (Livial or other)

Medicines against infections
Moxifloxacin (Izilox or other)

Medications for Alzheimer’s disease
Donepezil (Aricept or other)
Galantamine (Reminyl or other)
Rivastigmine (Exelon or other)
Memantine (Ebixa or other)

Medications for multiple sclerosis
Natalizumab (Tysabri)

Other drugs used in neurology
Fenfluramine (Fintepla)
Flunarizine (Sibelium)
Oxetorone (Nocertone)
Ginkgo biloba (Tanakan or other)
Naftidrofuryl (Naftilux or other)
Piracetam (Nootropyl or other)
Tolcapone (Tasmar)

cough medicine
Ambroxol (Muxol or other)
Bromhexine (Bisolvon)
Oxomemazine (Toplexil or other)
Pentoxyverine (Pentoxyverine Clarix 0.15%)

Sore throat medications
Alpha-amylase (Maxylase or other)
Tixocortol Oral Spray (Rhinadvil Sore Throat)
Drugs used in pulmonology and otorhinolaryngology
Oral and/or nasal decongestants: ephedrine, naphazoline, oxymetazoline, phenylephrine, pseudoephedrine, thuaminoheptane
Nintedanib (Ofev)

medications for depression
Agomelatine (Valdoxan or other)
Citalopram (Seropram)
Escitalopram (Seroplex or other)
Duloxetine (Cymbalta or other)
Milnacipran (Milnacipran Arrow or other)
Venlafaxine (Effexor LP or other)
Esketamine nasal spray solution (Spravato)
Tianeptine (Stablon or other)

Other psychotropics
Dapoxetine (Priligy)
Etifoxine (Stressam)

smoking cessation drugs
Bupropion (Zyban)

Drugs used in urology
Oral pentosan polysulfate (Elmiron)

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