How to explain and prevent the boom in allergies among children?

How to explain and prevent the boom in allergies among children?

Why does your baby vomit industrial milk? Why can’t your child go outside in May without having tears in their eyes? And why does your daughter feel short of breath as soon as she sleeps in a country house? Today, respiratory and food allergies affect many children…. And more and more The causes of these allergic diseases seem multiple and complex. Therefore, it seems essential to understand them better to avoid their explosion.

Allergies increased from 3.8% to 30% of the world population in fifty years

There is normally no reason why a human cannot tolerate herbs or peanuts from birth. It is an excessive immune reaction that explains the runny nose, red eyes, sneezing, swelling, scratching… “Allergies rank 4th among chronic diseases according to the World Health Organization, introduces Karine Adel-Patient, researcher at the Public Research Institute that works for the consistent and sustainable development of agriculture, food and the environment (Inrae). And the WHO predicts that 50% of the world population will suffer from allergies in 2050.” Because these pathologies, respiratory or food, have been constantly increasing for thirty years. The WHO estimates that 30% of the world’s population is affected by an allergic disease today, compared to 3.8% in 1968.

“Allergies are becoming more frequent and serious in children”

In France, the number of people suffering from allergies has doubled in twenty years, according to the associations. Without sparing the children. Although it is difficult to compare surveys that do not always have the same subject of study -for example, a single food or a single pollen- or the same population studied, several international and French studies have cause for alarm. The Elfe study, which follows 15,000 French children born in 2011, reveals that 6% of them have developed a food allergy and, among them, 20% have multiple allergies. “Allergies are becoming more frequent and serious in children, says Karine Adel-Patient. asthma [80 % des asthmes sont allergiques] It affects 4 million French people, a third of whom are children. Similarly, 6-8% of children suffer from food allergies…compared to 2-4% of adults. »

A concern confirmed by Madeleine Epstein, an allergist in Paris and vice president of the union of allergists (Syfal). “Objectively, there are more and more allergic children. When I became an allergist in the 1980s, we hardly ever talked about food allergies. In addition, it was with children that we discovered allergies to peanuts, milk… Today, the most common food allergic reactions in them are related to peanuts, tree nuts, eggs and milk. “With a significant impact on your daily life. “Allergies are the leading cause of school absenteeism, notes Karine Adel-Patient. A child allergic to milk will not be able to participate in birthday parties. »

Possible explanations for this increase in allergies

Is it the omnipresence of plastic in our environment? Chemical compounds in baby bottles? industrial food? The clothes ? The air pollution ? The causes are still very mysterious. “It is multifactorial, warns the allergist. The immune system is malfunctioning. Who orders it? The microbiota. However, changes in diet and environment influence it. We also know that the use of antibiotics modifies it, but there are more allergies in children who have received many small antibiotics. »

One clue also leads to global warming. Plants and trees grow where the population has never been exposed to this type of pollen. “Pollution acts on pollens making them more allergenic and on respiratory mucous membranes making them more fragile. In addition, it can modify the genome and make the propensity to be allergic hereditary. It works in all directions, it’s great! jokes Dr. Madeleine Epstein.

This explains why there are more and more allergic children, it is also that the genetic component is important. “In the general population, a child has between 5 and 10% risk of developing an allergy, but between 30 and 40% if one of their parents is allergic, and up to 60% if both are.” Karine Adel-Patient continues. . Logically, if more and more adults develop allergies and become parents, the proportion of allergic children increases.

How to determine the factors of these allergies and improve prevention?

To go further and understand the triggers, Karine Adel-Patient’s team at Inrae has launched a research project on the link between food and allergies in childhood. For five years and thanks to the support of the Foundation for Medical Research (FRM), attempts have been made to determine which chemical contaminants, ingested by the mother during pregnancy and lactation, could be responsible. The researchers draw on two major French epidemiological studies: Elfe, which we have already mentioned, and Eden, which focuses on the determinants of child development and health. “They follow the mothers during pregnancy to learn about their diet, their way of life,” explains the researcher. Then we take samples of milk, hair, urine in the maternity ward. Then her children are followed for ten to twenty years, particularly to see if they develop allergies. We will then cross these data with those of the National Food Safety Agency (Anses), which has published contamination levels for 400 foods that cover 90% of the average French diet. »

Additional Focus: The team is interested in meconium, the baby’s first bowel movement. “They accumulate during the last six months of pregnancy. History to examine what the fetus has ingested through the placenta. Finally, the researchers test certain contaminants on mice to see if their offspring develop allergies. The goal? “We hope to be able to highlight specific dangerous contaminants and help implement a prevention policy to curb the allergy epidemic”, concludes Karine Adel-Patient. In the meantime, what can expectant mothers do? The researcher advises them to “eat diversified fruits and vegetables, seasonal, as natural as possible, and avoid everything processed and packaged. Hoping to have much more specific recommendations ten years from now.

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